The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 1984
Filed:
May. 11, 1982
Applicant:
Inventors:
David R Brittain, Macclesfield, GB;
Robin Wood, Hazel Grove, GB;
Assignee:
Imperial Chemical Industries PLC, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
4242 / ; 424262 ; 546 10 ; 546 15 ; 546 84 ; 548101 ; 548309 ; 548431 ;
Abstract
The invention provides an aldose reductase inhibitory pyrrole derivative of the formula: ##STR1## in which Ra is an optionally substituted benzyl or cinnamyl radical, and ring A is the benzene ring of an optionally substituted benzo[b]thiophene, benzo[b]furan, quinoline or N-alkylquinolone, together with pharmaceutically acceptable salts and non-toxic biodegradable precursors thereof. The compounds of formula I are useful in the treatment of prophylaxis of the side-effects of diabetes or galactosemia.