The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 1984
Filed:
Jun. 03, 1982
Yoshikazu Isowa, Tokyo, JP;
Muneki Ohmori, Tokyo, JP;
Kaoru Mori, Sagamihara, JP;
Tetsuya Ichikawa, Sagamihara, JP;
Yuji Nonaka, Shin-Nanyo, JP;
Keiichi Kihara, Shin-Nanyo, JP;
Kiyotaka Oyama, Shin-Nanyo, JP;
Heijiro Satoh, Shin-Nanyo, JP;
Shigeaki Nishimura, Shin-Nanyo, JP;
Toyo Soda Manufacturing Co., Ltd., Shin-Nanyo, JP;
Sajami Chemical Research Center, Tokyo, JP;
Abstract
Addition compounds have the formula ##STR1## wherein R.sub.1 represents an aliphatic oxycarbonyl group, benzyloxycarbonyl group which can have nuclear substituents or benzoyl, aromatic sulfonyl or aromatic sulfinyl group; R.sub.2 represents methyl, isopropyl, isobutyl, isoamyl or benzyl group; R.sub.3 represents a lower alkoxyl, benzyloxy or benzhydryloxy group and n represents 1 or 2. The addition compounds are produced by reacting an N-substituted monoaminodicarboxylic acid having the formula ##STR2## with an amino carboxlic acid ester having the formula in an aqueous medium in the presence of a protease and reacting the resulting dipeptide ester with the amino carboxylic acid ester and separating the addition compound. The addition compounds can be decomposed into the constituent dipeptide esters and amino acid esters by the action of an acid.