The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 1984
Filed:
Feb. 17, 1982
Werner P Vollenberg, Stolberg, DE;
Horst R Boehlke, Stolberg, DE;
Gruenenthal GmbH, Stolberg, DE;
Abstract
The invention relates to a process for the preparation of 2-Oxabicyclo[3.3.0]octane derivatives of the general formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.5 represent organic radicals and R.sub.2 and R.sub.3 also may represent hydrogen and wherein R.sub.4 is an acyl group or an tri-organo-silyl group and to the compounds of formula I produced by the process of the invention which compounds are valuable intermediates for the preparation of pharmacologically active compounds. The process of the invention comprises reacting a compound of the formula ##STR2## wherein R.sub.14 is lower alkyl or phenyl with a compound of the formula ##STR3## wherein R.sub.15 is trimethylsilyl or lower alkanoyl in an inert solvent at temperatures from about -80.degree. C. to about +60.degree. C. in presence of one or more Lewis acids.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile