The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 1984

Filed:

May. 07, 1982
Applicant:
Inventors:

Hamao Umezawa, Tokyo, JP;

Tomio Takeuchi, Tokyo, JP;

Shinichi Kondo, Yokohama, JP;

Hironobu Iinuma, Tokyo, JP;

Daishiro Ikeda, Tokyo, JP;

Teruya Nakamura, Kusatsu, JP;

Akio Fujii, Kamakura, JP;

Assignee:

Bristol-Myers Company, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ;
U.S. Cl.
CPC ...
424311 ; 424308 ; 424312 ; 424320 ; 560251 ; 560110 ; 564159 ; 2604045 ;
Abstract

The novel compound represented by the general formula (I) ##STR1## (wherein R represents a hydrogen atom, an alkanoyl group of 1 to 14 carbon atoms, or an arylcarbonyl group), and an acid addition salt thereof [on condition that when R is a hydrogen atom, the hydrochloride exhibits an optical rotation of [.alpha.].sub.D.sup.22 -1.degree. .+-.2.degree. (c, 2 water)] has antitumor activity in experimental animals.


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