The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 1984
Filed:
Jun. 08, 1981
Applicant:
Inventor:
Surendar Jain, Watertown, MA (US);
Assignee:
Ionics, Incorporated, Watertown, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A23J / ; A23K / ; C07G / ; G12P / ;
U.S. Cl.
CPC ...
2601 / ; 2041 / ; 2041 / ; 204301 ; 424 85 ; 424177 ; 435 68 ; 435811 ;
Abstract
A process is described for the selective recovery and/or concentration of a protein or a class of proteins from fermentation broth employing a combination of desalting and pH adjustment thereby causing the initial precipitation of unwanted proteins, again subjecting the resulting supernatant to another set of pH adjustment and desalting to cause the protein of interest to precipitate thereby obtaining a highly enriched fraction of the selected protein. Such a process will find use in the specific recovery of genetically engineered proteins from fermentation broths, e.g. interferon, insulin, growth hormone, etc.