The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 1984

Filed:

Nov. 10, 1981
Applicant:
Inventors:

Axel Kleemann, Hanau, DE;

Marc Samson, Hanau, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
549373 ; 549452 ; 548309 ;
Abstract

The invention is directed to a cyclic acetal of N-acylglutamic acid-.gamma.-semialdehyde of the formula ##STR1## in which A is an unsubstituted alkylene group having 2 to 3 carbon atoms or such an alkylene group substituted by 1 to 2 methyl groups and R is a methyl, methoxy, phenyl, or benzyloxy group and to a method of producing a compound of formula (I) by reaction of a compound of the general formula ##STR2## in which A is as defined above, with hydrogen cyanide or a cyanide ion supplying compound, ammonia or an ammonium ion supplying compound and carbon dioxide or a carbonate ion supplying compound and basic hydrolysis of the reaction mixture obtained and reaction of the hydrolysis mixture with a suitable acylating compound and use of the compounds of formula (I) to produce .alpha.-N-acyltryptophane.


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