The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 1983
Filed:
Apr. 16, 1981
Applicant:
Inventors:
A Michael Albisser, Toronto, CA;
William D Lougheed, Toronto, CA;
Assignee:
The Hospital for Sick Children, Toronto, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ; C07G / ;
U.S. Cl.
CPC ...
424178 ; 2601 / ; 2601127 ; 424177 ;
Abstract
The present invention is directed to a solution of a polypeptide, such as, for example, insulin, the solution being prepared and maintained at pH 6.8 to 8.0 and in which the polypeptide remains in solution in disaggregated form. This is accomplished by the use of the bicarbonate ion in the solution, the bicarbonate ion being present in a concentration of 2 mmolar to 2.5 molar. A method for preparing the polypeptide solution and the use of the solution in maintaining normoglycemia are provided.