The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 1983
Filed:
Feb. 04, 1982
Tibor Keve, Budapest, HU;
Gyorgy Fekete, Budapest, HU;
Csaba Lorincz, Budapest, HU;
Janos Galambos, Erd, HU;
Bela Zsadon, Budapest, HU;
Maria Zajer nee Balazs, Budapest, HU;
Lilla Forgach, Budapest, HU;
Egon Karpati, Budapest, HU;
Arpad Kiraly, Budapest, HU;
Gyongyver Kiraly nee Soos, Budapest, HU;
Laszlo Szporny, Budapest, HU;
Bela Rosdy, Budapest, HU;
Richter Gedeon Vegyeszeti Gyar RT, Budapest, HU;
Abstract
The present invention relates to the compounds of the Formulae 1a and 1b and pharmaceutically acceptable acid addition salts thereof. The new 9-nitro-apovincaminol-3',4',5'-trimethoxybenzoate of the Formula 1a ##STR1## and the 11-nitro-apovincaminol-3',4',5'-trimethoxy-benzoate of the Formula 1b ##STR2## and pharmaceutically acceptable acid addition salts thereof can be prepared by nitrating the apovincaminol-3',4',5'-trimethoxy-benzoate of the Formula 11, ##STR3## if desired separating the mixture of the compounds of the Formulae 1a and 1b thus obtained into its components, if desired converting a compound of the Formula 1a or 1b thus obtained into pharmaceutically acceptable acid addition salts thereof. The new compounds of the present invention can be used in therapy in the treatment of psoriasis.