The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 15, 1983

Filed:

Mar. 05, 1980
Applicant:
Inventors:

Harry P Zhabilov, Razgrad, BG;

Todor Y Karavassileff, Razgrad, BG;

Assignee:

DSO 'Pharmachim', Sofia, BG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C12P / ; C12P / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
424 95 ; 424177 ; 424180 ; 435 68 ; 435 69 ; 435172 ; 435240 ; 2601 / ; 2601 / ;
Abstract

The invention comprises preparations for the treatment of neoplasms, the methods of treatment of neoplasms using such preparations, and processes for preparing such preparations, including the step of selective enzymatic degradation of the nuclei of cancer cells. The invention further comprises the method of treating patients suffering from neoplasms with immunomodulating agents obtained by isolating the genetically active components of cancer cell nuclei obtained from cancer tissue, subsequently recombining them by specific hybridization steps to prepare a vaccine therefrom, and intravenously, intraperitoneally and/or intramuscularly administering the resulting vaccine product to patients. The neoplastic tissue used may be obtained by surgical removal either from the diseased portion of the patient's body who suffers from the neoplasm or from another patient who suffers from the same or similar type and form of neoplasm as the patient to be treted by said method, or from tumors transplanted into animals or from virus-, chemically-, irradiation-caused tumors in animals or from spontaneous tumors in animals.


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