The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 15, 1983

Filed:

Feb. 20, 1981
Applicant:
Inventor:

Beniamino Palmieri, Modena, IT;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B26F / ;
U.S. Cl.
CPC ...
225 935 ; 225-1 ; 241D / ; 356 36 ;
Abstract

An apparatus for intraoperative diagnosis is described which comprises a refrigerating device adapted to sprinkle a cryogenic liquid on the surface of a slide whereby the surface of the slide is cooled to at least -4.degree. C. up to -8.degree. C., at least one cooling fan which increases the evaporation of the cryogenic liquid and permits to achieve the necessary hypothermia on the slide; an automatic appositor which permits to exert a measurable and graduated pressure onto the section of the organ which has been interposed between the appositor and the slide at the time in which the section has reached a predetermined temperature. The appositor is provided with means for varying automatically the pressure during the advance of the slide. The refrigerating device comprises a cylinder containing a cryogenic liquid. The invention also resides in the method of carrying out histological analysis which consists of placing a section of tissue under examination on a slide, cooling vigorously the slide whereby the tissue undergoes a thermic shock and exfoliates on the slide. Pressure is applied after the section of tissue has been cooled.


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