The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 1983
Filed:
Sep. 25, 1981
Bayer Aktiengesellschaft, Leverkusen, DE;
Abstract
A process has been developed for the preparation of compounds of the formula ##STR1## wherein R is hydrogen or an optionally substituted alkyl radical, which comprises reacting glucose with a compound of the formula H.sub.2 N-R wherein R has the meaning given above to form a 1-amino-sorbitol of the formula ##STR2## wherein R has the meaning given above, reacting said 1-aminosorbitol with a compound providing a protective group which can be split off under acid conditions and is stable in the subsequent microbiological oxidation process, aerobically oxidizing the compound thus obtained microbiologically to give a protected 6-aminosorbose, splitting off the protective group under acid conditions and hydrogenating the 6-aminosorbose salt thus obtained either after being isolated or in one operation, to give the compound of the formula (I). The products obtained by the process of the invention are useful as .alpha.-glucoside inhibitors.