The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 1983

Filed:

Dec. 17, 1981
Applicant:
Inventors:

Jean Bouchaudon, Morsang-sur-Orge, FR;

Gilles Dutruc-Rosset, Paris, FR;

Daniel Farge, Thiais, FR;

Claude James, Paris, FR;

Assignee:

Rhone-Poulenc Sante, Courbevoie, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ;
U.S. Cl.
CPC ...
424177 ; 2601 / ;
Abstract

The invention provides tri-, tetra- or penta-peptides of the general formula: ##STR1## in which RCO is a fatty acid residue, R.sub.1 is hydroxyl, amino, alkoxy or benzyloxy, R.sub.2 and R.sub.4 (identical or different) represent hydrogen, carboxyl, alkoxycarbonyl or benzyloxycarbonyl or an optionally esterified N-carbonylglycyl or N-carbonyl-D-alanyl radical, it being impossible for R.sub.2 and R.sub.4 simultaneously to represent hydrogen, R.sub.3 is hydrogen, or represents a glycyl or D-alanyl residue (in which case, only one of the radicals R.sub.2 and R.sub.4 can represent an N-carbonylglycyl or N-carbonyl-D-alanyl radical), X is a sulphur atom or methylene, and m and n=1 or 2, it being understood that if X is methylene, m and n are different from 1, their salts, their preparation and compositions containing them: the compounds are useful as vaccine adjuvants or as non-specific stimulants of anti-infectious or anti-tumoral activity.


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