The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 1983

Filed:

Mar. 05, 1981
Applicant:
Inventors:

Hirotada Yamada, Nishinomiya, JP;

Kiyokazu Jimpo, Moriguchi, JP;

Takao Okuda, Toyonaka, JP;

Hiroshi Noguchi, Ashiya, JP;

Hisao Tobiki, Kobe, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
424246 ; 544 27 ;
Abstract

Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or a (C.sub.1 -C.sub.4) alkyl group, X is a straight or branched chain C.sub.1 -C.sub.4 alkylene group and R.sub.2 is a carboxyl group or a sulfo group; and the pharmaceutically acceptable salts thereof exhibit strong inhibitory activities against a wide variety of Gram-positive and Gram-negative bacteria including Psendomonas aeruginosa, indolepositive Proteus and Enterobacter aerogenes, and also have an increased and prolonged serum level in a living body. The compounds are therefore useful as antibacterial agents for the treatment of infectious diseases caused by Gram-positive and Gram-negative bacteria.


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