The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 1983
Filed:
May. 21, 1981
Teijin Limited, Osaka, JP;
Abstract
A reactive polymer having the degree of polymerization in the range of 5 to 3,000, with 60 mole % or more of the whole constituent units comprising the constituent units expressed by formula (I) ##STR1## wherein Z indicates a hydrogen atom or a univalent cation; m is an integer 1 to 4: and has an active group expressed by formula (II) at the carboxyl end of the main chain ##STR2## wherein X indicates a hydrogen atom or a group which can form an active disulfide linkage together with a neighboring sulfur atom; W is a divalent organic group; and R.sub.1 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms. Since this reactive polymer can bind to cytotoxic substances, which contain an amino group or imino group in the molecule by way of the carboxyl group of the side chain and it also can bind to, for instance, antitumor immunoglobulins by way of an active group (thiol group or active disulfide group) at the end of the main chain, it can be used as a polymer carrier in the preparation of target seeking antitumor drugs.