The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 1983
Filed:
Aug. 12, 1981
Applicant:
Inventors:
Frank J Mannuzza, Peotone, IL (US);
Joseph G Montalto, Bradley, IL (US);
Assignee:
Miles Laboratories, Inc., Elkhart, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07G / ;
U.S. Cl.
CPC ...
2601 / ; 424101 ;
Abstract
A method for removing pyrogenic material from bovine thrombin is disclosed. The method involves forming a complex of a blue dye and a polysaccharide and equilibrating the complex with a low ionic strength salt solution. Bovine thrombin is added to the complex. The pyrogenic material is removed from the bovine thrombin by washing the bovine thrombin with a low ionic strength salt solution, and the pyrogen-free bovine thrombin is recovered.