The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 1983

Filed:

Dec. 17, 1981
Applicant:
Inventors:

Kiyohiko Ito, Tama, JP;

Masuo Koizumi, Tokyo, JP;

Yasushi Murakami, Tokyo, JP;

Michitaka Akima, Sakado, JP;

Jinichiro Aono, Kawasaki, JP;

Yasuhiro Ohba, Kawasaki, JP;

Tamotsu Yamazaki, Tokorozawa, JP;

Kazushige Sakai, Tokyo, JP;

Shun-ichi Hata, Yokohama, JP;

Shigeru Takanashi, Asaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
424244 ; 42424854 ; 424250 ; 424267 ; 424274 ; 2602 / ;
Abstract

Dibenz[b,f][1,4]oxazepine derivatives of the formula ##STR1## (wherein R.sub.1 is a hydrogen atom or a lower alkyl group; R.sub.2 is a branched lower alkyl group; R.sub.3 is a hydrogen atom, a carboxyl group, a carbamoyl group, a lower alkoxycarbonyl group, or a lower alkoxy group; R.sub.4 and R.sub.5 are each a lower alkyl group or may, when taken together with a nitrogen atom, form a heterocyclic ring; and A is a lower alkylene group) or salts thereof, a process for preparing the same and pharmaceutical compositions comprising the same are disclosed. The derivatives of the formula above are effective to prevent and treat circulatory diseases, especially angina pectoris, and therefore, useful as medicines.


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