The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 1983

Filed:

Apr. 11, 1980
Applicant:
Inventors:

Thomas A Davis, Scotch Plains, NJ (US);

William J Asher, Fanwood, NJ (US);

Assignee:

Exxon Research and Engineering Co., Florham Park, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J / ; A01N / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
252316 ; 424 36 ; 424177 ;
Abstract

A process for preparing artificial red cells comprising microdroplets of aqueous, stroma-free hemoglobin solution encapsulated in membranes of polymerized hemoglobin, said process comprising forming microdroplets of hemoglobin solution in a continuous oil phase, cross-linking the hemoglobin at the surface of the microdroplets with a suitable cross-linking agent to form the artificial red cells and recovering the cells. In one embodiment, a liquid membrane encapsulation technique employing a water-soluble cross-linking agent is used to form the cells. In another embodiment an oil-soluble cross-linking agent is present in the oil phase containing the hemoglobin microdroplets.


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