The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 1983
Filed:
Oct. 14, 1981
Degussa Aktiengesellschaft, Frankfurt, DE;
Abstract
There are produced peptides by asymmetrical hydrogenation of dehydropeptides of the general formula ##STR1## in which n is a whole number from 1 to 4, R.sub.1 and R.sub.2 are the same or different, and are hydrogen, a straight or branched chain alkyl group with 1 to 10 carbon atoms, or such a group substituted with a carboxyl group, a phenyl group which is unsubstituted or substituted in the 3 or 4 position or in both the 3 and 4 positions by a hydroxyl, alkoxy, or acyloxy group or an indolyl group which is unsubstituted or substituted in the 6 position by fluorine or chlorine or an indolyl group substituted by a methyl group. R.sub.3 is hydrogen, an alkali metal, or a lower alkyl group with 1 to 4 carbon atoms, R.sub.4 is hydrogen, an acetyl group or a chloroacetyl group and R.sub.5 is hydrogen or a straight or branched chain alkyl group having 1 to 4 carbon atoms with the proviso that when n is 2, 3, or 4, the individual groups R.sub.5 are the same or different, in the presence of chiral rhodium-complexes.