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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 4360684 B1

PDFFull Text
Date of Patent:
Nov. 23, 1982

Filed:

Apr. 08, 1981

Process for the preparation of

Applicant:
Inventors:

Raymond J Cvetovich, Roselle Park, NJ (US);

David G Melillo, Scotch Plains, NJ (US);

Kenneth M Ryan, Clark, NJ (US);

Meyer Sletzinger, North Plainfield, NJ (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:

Pfeiffer; Hesna J.

Arno; James A.

Primary Examiner:

Jane T Fan

Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
549291 ; 2602 / ; 2602 / ; 548453 ; 560171 ;
Abstract

Disclosed is a process for preparing (2S)-tetrahydro-2.alpha.-methyl-6-oxo-4.beta.-amino-2H-pyran-3.alpha.-carb oxylic acid (I) which is useful in the synthesis of thienamycin. The process proceeds via a stereospecific reduction of the 2-acetyl-3-(R)-.alpha.-methylbenzylamino-2-pentenedioic acid diester (II). ##STR1## wherein R is, .alpha.-methylbenzyl, and R.sup.1 is lower alkyl having 1-6 carbon atoms or arylalkyl such as benzyl.

Find Patent Forward Citations

Cvetovich, Raymond. (1982). Process for the preparation of (U.S. Patent No. 4360684). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4360684

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