The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 1982
Filed:
Jul. 01, 1981
Dietmar P Rabussay, Gaithersburg, MD (US);
Interon, Inc., Potomac, MD (US);
Abstract
A dental and gum treatment agent and method uses the isolated and purified enzyme species lysozyme as a primary active substance to attack and destroy in situ the cariogenic bacteria in the oral cavity forming the plaque-calculus substrate and causing gum disorders. The agent operates to penetrate the bacterial cell wall and thereby destroy existing bacteria by disintegration so that residues are washed away. Auxiliary isolated enzymes of the groups of lipases, carbohydrases, phospholipases and proteases are used as additives to decrease treatment time as an aid to penetration of cell walls of gram (-) type bacteria. EDTA (ethylene diamino tetraacetic acid) is also used as an additive to remove ionic bonds that could clamp and stabilize bacterial walls to some extent after the lysozyme action. Thus, an aqueous solution of about 0.1 mg/ml of isolated lysozyme with or without controlled addition of known additives is effective in an oral cavity application for a few minutes to treat dental caries by removal of plaque and calculus, and to control gum infections.