The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 1982

Filed:

Jan. 15, 1981
Applicant:
Inventors:

Paul Fabiani, Neuilly, FR;

Francis Rose, Paris, FR;

Abkar Vartanian, Amilly, FR;

Christian Warolin, Paris, FR;

Assignee:

Synthelabo, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
424250 ; 544236 ; 544238 ; 544224 ;
Abstract

2,3-Dihydro-imidazo[1,2-b]pyridazine derivatives of the formula: ##STR1## in which R.sub.1 represents a phenyl, halogenophenyl, trifluoromethylphenyl, C(.sub.1-4)-alkylphenyl, (C.sub.1-4)-alkoxyphenyl, hydroxyphenyl, nitrophenyl, aminophenyl, (C.sub.1-4)-alkylaminophenyl, di-(C.sub.1-4)-alkylaminophenyl, acetamidophenyl, thienyl, pyridyl, furyl or nitrofuryl radical, R.sub.2 represents a hydrogen atom or a (C.sub.1-4)-alkyl radical, and R.sub.3 represents a hydrogen atom or a (C.sub.1-4)-alkyl, phenyl, halogenophenyl, trifluoromethylphenyl, (C.sub.1-4)-alkylphenyl, (C.sub.1-4)-alkoxyphenyl, hydroxyphenyl, nitrophenyl, aminophenyl, (C.sub.1-4)-alkylaminophenyl, di-(C.sub.1-4)-alkylaminophenyl or acetamidophenyl radical, and its addition salts with pharmaceutically acceptable acids are useful in therapy as antidepressants. They may be made by cyclization of compounds of the formula: ##STR2##


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