The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 05, 1982

Filed:

Mar. 28, 1979
Applicant:
Inventor:

Franklin Lim, Richmond, VA (US);

Assignee:

Damon Corporation, Needham Heights, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435178 ; 3-1 ; 264-4 ; 424 34 ; 424 35 ; 424 94 ; 435-1 ; 435175 ; 435182 ; 435240 ;
Abstract

A core material such as living tissue, individual cells, hormones, enzymes or antibodies is encapsulated in a semipermeable membrane that is permeable to small molecules for contact with the core material but is impermeable to potentially deleterious large molecules. Encapsulation may be carried out by suspending the core material in an aqueous medium containing a water soluble gum that can be reversibly gelled, forming the suspension into droplets, contacting the droplets with a solution of multivalent cations to gel the droplets as discrete, shape-retaining, water insoluble temporary capsules and cross-linking a surface layer of the temporary capsules to produce a semipermeable membrane around the capsules. Optionally the gel within the membrane may be reliquified by removing multivalent cations from the gel.

Published as:
BE882476A; DK130580A; NO800901L; SE8002357L; FR2452285A1; GB2046209A; DE3012233A1; JPS55157502A; FR2457688A1; US4352883A; CA1145258A; GB2046209B; CH653914A5; IT1133081B; CH657786A5; FR2452285B1; FR2457688B1; JPS61293919A; SE448060B; JPS6239131B2; JPS6242889B2; DE3012233C2; NO160380B; NO160380C;

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