The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 1982

Filed:

Aug. 06, 1981
Applicant:
Inventors:

Frederic P Hauck, Bridgewater, NJ (US);

Rita T Fox, Princeton, NJ (US);

Assignee:

E. R. Squibb & Sons, Inc., Princeton, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ; C07D / ;
U.S. Cl.
CPC ...
544 79 ; 2602 / ; 2602 / ; 2602457 ; 260330 ; 544 584 ; 544357 ; 546187 ; 546189 ; 548200 ; 548215 ; 548300 ; 548518 ; 564156 ; 549433 ;
Abstract

Compounds are provided having the structure ##STR1## wherein R.sup.1 and R.sup.2 may be the same or different and are hydrogen, lower alkyl, lower alkenyl, or hydroxylower alkyl, or R.sup.1 and R.sup.2 together with the nitrogen atom to which they are attached also form a heterocyclic radical which may contain another heteroatom, namely nitrogen, oxygen or sulfur; R.sup.3 and R.sup.4 may be the same or different and are hydrogen or lower alkyl. These compounds are useful in the treatment of arrhythmia. In addition, novel intermediates are provided having the structure ##STR2## wherein R is hydrogen, benzyl or ##STR3## These intermediates are also useful in treating acute myocardial infarction.


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