The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 1982

Filed:

Nov. 29, 1979
Applicant:
Inventors:

Roger Crossley, Reading, GB;

David G Hill, Cookham, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
424263 ; 546275 ; 546278 ; 546290 ;
Abstract

Novel compounds of formula I ##STR1## are described wherein R is lower alkyl, phenyl or aralkyl of 7 to 12 carbon atoms, R.sup.1 is hydrogen, lower alkyl, hydroxyloweralkyl, loweralkoxyloweralkyl, lower alkoxy, halogen, formyl, phenyl, phenylalkyl or acetal [CH(OR.sup.2).sub.2 where R.sup.2 is lower alkyl, or two R.sup.4 radicals are joined to form a lower alkylene chain], m is 1 or 2, Z is an anion, A is an alkylene radical having from 1 to 3 carbon atoms, which may be substituted by lower alkyl of 1 to 6 carbon atoms, S is sulphur and X is a benzothiazole, benzimidazole, benzoxazole, or phenyl radical which may be substituted and acid addition or quaternary ammonium salts of compounds wherein X is a benzimidazole radical. The compounds are used for the treatment of ulcers or hypersecretion. Treatment methods are claimed as well as pharmaceutical compositions.


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