The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 1982

Filed:

Sep. 26, 1979
Applicant:
Inventor:

Peter R Marsham, Poynton, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ;
U.S. Cl.
CPC ...
424250 ; 562465 ; 562471 ; 2605011 ; 562470 ; 564 52 ; 26050113 ; 564169 ; 564189 ; 26050115 ; 568 31 ; 568 32 ; 544235 ; 568630 ; 568632 ; 544283 ; 568634 ; 568656 ; 544349 ; 424251 ; 424256 ; 544356 ; 424258 ; 424269 ; 546339 ; 424274 ; 424286 ; 546341 ; 424308 ; 424309 ; 546344 ; 548460 ; 548454 ; 546176 ; 549407 ; 549435 ; 548250 ; 549437 ; 549466 ; 548253 ; 548484 ; 548486 ; 549 49 ; 549 58 ; 549355 ; 549399 ; 560 21 ; 560 24 ; 560 32 ; 560 55 ; 560 60 ; 560106 ; 560111 ; 560115 ; 560162 ; 562434 ; 562438 ; 562452 ; 562455 ;
Abstract

The disclosure relates to 9.beta.-aryloxy prostane derivatives, for example 16-(3-chlorophenoxy)-11.alpha.,15.alpha.-dihydroxy-16-methyl-9.beta.-pheno xy-18,19,20-trinor-5-cis,13-trans-prostadienoic acid, which possess high activity as abortifacients, cervical softeners, inducers of parturition or inhibitors of gastric acid production in mammals. These properties are typical of prostaglandin analogues of the E series, but chemically the new 9.beta.-aryloxy prostane derivatives are prostaglandin F series analogues and are therefore more stable than the E series analogues previously used for the above purposes. The new derivatives are manufactured by known analogy processes, and are formulated in conventional manner.


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