The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 1982
Filed:
Jan. 03, 1980
Applicant:
Inventors:
Charles D Kimball, Seattle, WA (US);
John C Houch, Seattle, WA (US);
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07G / ; C07C / ; A61K / ;
U.S. Cl.
CPC ...
424177 ; 2601 / ; 2601 / ;
Abstract
A peptide endorphin having a molecular weight in the range of about 4500 to 5000 daltons is described. This peptide endorphin has .beta.-endorphin-like activity, reacting immunologically to rabbit antisera prepared against .beta.-endorphin and displacing Naloxone from opiate receptors in brain tissue. Unlike .beta.-endorphin, however, this peptide endorphin does not exhibit respiratory depressor effect when administered to mice. This peptide endorphin can be obtained from placental and pancreatic tissue, preferably by extracting with dilute mineral acid.