The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 1982
Filed:
Dec. 10, 1979
Tai-Wing Wu, Rochester, NY (US);
Eastman Kodak Company, Rochester, NY (US);
Abstract
A method is described for the separation and isolation of conjugated and unconjugated bilirubin from an aqueous liquid containing one or both of the bilirubin components. The aqueous liquid is contacted together with an interactive mordant for bilirubin to mordant bilirubin, the mordanted bilirubin is separated from the aqueous liquid, and the mordanted bilirubin is treated in an aqueous medium with a chaotropic agent at least slightly soluble in the medium to release the conjugated and/or unconjugated bilirubin from the mordant. A preferred embodiment also provides for selectively separating conjugated bilirubin from unconjugated bilirubin by selectively solubilizing either the conjugated or unconjugated bilirubin released from the mordant. Isolated conjugated bilirubin is thereby obtained having a purity in excess of 75%. A reference composition comprising the isolated conjugated bilirubin is also disclosed.