The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 1981

Filed:

Jan. 07, 1980
Applicant:
Inventors:

Ralph J De Pasquale, Gainesville, FL (US);

Paul D Schuman, Hawthorne, FL (US);

Assignee:

PCR, Incorporated, Gainesville, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
544334 ; 544313 ;
Abstract

A process for preparing 5-fluorouracil, and a novel starting compound for such process, are disclosed. The novel starting compound is 2,4,5-trifluoropyrimidine. The process comprises hydrolyzing the 2,4,5-trifluoropyrimidine at a temperature of about 2.degree. to about 100.degree. C., thereby directly producing the compound 5-fluorouracil. 5-fluorouracil is a known anti-tumor agent, which has been used in the treatment of various types of cancers. In addition, 5-fluorouracil is a starting material for the production of certain types of pro-drugs, which are metabolized to form 5-fluorouracil in the body, such as, for instance, the compound 1-(2-tetrahydrofuryl)-5-fluorouracil.


Find Patent Forward Citations

De Pasquale, Ralph. (1981). 2,4,5 trifluoro pyrimidine and process for preparing (U.S. Patent No. 4299961). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4299961

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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