The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 1981
Filed:
Dec. 10, 1979
Applicant:
Inventors:
Robert B Woodward, Cambridge, MA (US);
Hans Bickel, Binningen, CH;
Assignee:
Ciba-Geigy Corporation, Ardsley, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
2602 / ; 546208 ; 546209 ; 544 60 ; 546210 ; 546212 ; 544 62 ; 546213 ; 546214 ; 544111 ; 546256 ; 546270 ; 544131 ; 546271 ; 546275 ; 544133 ; 546276 ; 546277 ; 544134 ; 546278 ; 546280 ; 544135 ; 546281 ; 546283 ; 544137 ; 546284 ; 544 16 ; 544138 ; 544 30 ; 546207 ; 544139 ; 544140 ; 544146 ; 544149 ; 544152 ; 544337 ; 544359 ; 544364 ; 544366 ; 544367 ; 544368 ; 544369 ; 544370 ; 544374 ; 544379 ; 2602454 ; 2603303 ; 2603474 ; 546193 ; 546194 ; 546198 ; 546199 ; 546205 ;
Abstract
The invention concerns a process for the manufacture of 7.beta.-amino-3-cephem-3-ol-4-carboxylic acid compounds by ring closure of esters of 2-[4-(substituted-thio)-3-acylamino-2-oxoazetidin-1-yl]-3-substituted-amin o-crotonic acids and solvolyzing the enamino group in the resulting 7.beta.-acylamino-3-substituted-amino-cephem-4-carboxylic acid esters.