The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 1981
Filed:
Nov. 13, 1979
Albert Szent-Gyorgyi, Woods Hole, MA (US);
Gabor B Fodor, Morgantown, WV (US);
National Foundation for Cancer Research, Bethesda, MD (US);
Abstract
Novel cyclic acetals of the general formulae: ##STR1## wherein R.sub.1 is ##STR2## wherein R.sub.2 is hydrogen, alkyl, aryl or R.sub.1, wherein R.sub.3 through R.sub.10 are hydrogen, alkyl or aryl, wherein R.sub.5 and R.sub.6 together may form .dbd.O, wherein X is hydrogen, alkyl, cycloalkyl, aryl, hydroxyaryl or arylakyl, or wherein R.sub.8 is ##STR3## are described. Said compounds are prepared by mixing approximately equimolar amounts of the appropriate aldehyde or ketone, and enediol compound, and allowing same to react in aqueous solution under a nitrogen atmosphere. Compositions containing these novel compounds exhibit hypotensive and analgesic properties and are useful in the treatment of hypertension and pain in animals and humans.