The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 1981

Filed:

Jul. 23, 1979
Applicant:
Inventors:

Raphael Mechoulam, Jerusalem, IL;

Naphtali Lander, Tel-Aviv, IL;

Shabtay Dikstein, Jerusalem, IL;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
424299 ; 424346 ; 560141 ; 560255 ; 568734 ;
Abstract

The present invention relates to novel compounds of the general formula ##STR1## wherein R.sup.1 is --H or --CO--alk, wherein alk is lower alkyl of 1 to 5 carbon atoms; R.sup.2 is 1,1-dimethylheptyl or 1,2-dimethylheptyl, Q is --CH.sub.3 when A------B is a single bond, and Q is --CH.sub.2 OR.sup.4 when A------B is a double bond, and R.sup.4 is --H or --CO--alk where alk is lower alkyl of 1 to inclusive 5 carbon atoms. The invention relates both to the isomeric mixtures and to the individual isomers of the above compounds. Furthermore the invention relates to pharmaceutical compositions containing a compound defined above as active ingredient. The pharmaceutical compositions are of value as central nervous system depressants, as sedatives, as tranquilizers, as anticonvulsant agents, as effective agents against migraine, for the treatment of glaucoma, as antidiarrheal agents and as antiinflammatory agents. The invention also relates to a process for the production of the above compounds and pharmaceutical compositions.


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