The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 1981
Filed:
Mar. 31, 1980
Applicant:
Inventor:
Jeffrey L Ives, King of Prussia, PA (US);
Assignee:
Pfizer Inc., New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
424263 ; 424274 ; 424275 ; 424285 ; 546281 ; 546306 ; 546332 ; 549 65 ; 26032685 ; 2603477 ;
Abstract
A series of phenylguanidine base compounds and their pharmaceutically acceptable acid addition salts have been found to be active as oral hypoglycemic agents. Preferred member compounds include N,N'-diphenyl-1-pyrrolidinocarboxamidine, N-phenyl-N'-methyl-N'-phenyl-1-pyrrolidinocarboxamidine and N-phenyl-N'-(p-chlorophenyl)-1-pyrrolidinocarboxamidine, and their hydrohalide acid addition salts. Synthetic routes leading to these compounds are described.