The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 1981

Filed:

Jun. 24, 1980
Applicant:
Inventors:

Ludovic Rodriguez, Brussels, BE;

Jacques Leclercq, Braine l'Alleud, BE;

Pierre Ykman, Brussels, BE;

Eric Cossement, Brussels, BE;

Assignee:

U C B Societe Anonyme, Saint-Gilles-lez-Bruxelles, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
424267 ; 546 17 ; 548147 ; 2602 / ;
Abstract

6-Amino-spiro[penam-2,4'-piperidine]-3-carboxylic acids, salts and esters thereof of the formula ##STR1## wherein R.sub.1 is hydrogen, benzyl or an alkali metal or ammonium ion and R.sub.2 is methyl, phenyl or benzyl and process for preparing the same. These compounds are useful as intermediates in the synthesis of a new group of antibiotics having properties similar to penicillins, besides own antibiotic activity with a broad antibacterial spectrum. Therefore, they are useful as antibacterials agents and as therapeutic agents for humans and for animals in the treatment of infectious diseases caused by Gram-positive and Gram-negative bacteria.


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