The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 1981
Filed:
Aug. 15, 1979
Applicant:
Inventors:
Assignee:
Gist Brocades N.V., Delft, NL;
Primary Examiner:
Int. Cl.
CPC ...
C07J / ; C07J / ;
U.S. Cl.
CPC ...
26023957 ; 2602395 ; 2602 / ;
Abstract
A process is disclosed for the preparation of 17.beta.-hydroxy-3-oxo-l7.alpha.-pregn-4-ene-21-carboxylic acid .gamma.-lactone and 17.beta.-hydroxy-3-oxo-17.alpha.-pregna-4,6-diene-21-carboxylic acid .gamma.-lactone of the formula: ##STR1## wherein the dotted line between the 6-7 positions indicates an optional double bond, which is present in the latter compound, by reacting an androst-5-ene-17-one derivative with an organo-phosphorus compound. These lactones are valuable intermediates in the synthesis of spironolactone.