The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 1981
Filed:
Nov. 13, 1979
Applicant:
Inventors:
Osamu Miyashita, Osaka, JP;
Hiroshi Akimoto, Nishinomiya, JP;
Assignee:
Takeda Chemical Industries, Ltd., Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
42424854 ; 2602 / ;
Abstract
Novel maytansinoids of the formula: ##STR1## wherein X is H or Cl, and R is ##STR2## wherein R.sup.1 and R.sup.2 may be the same or different, and each is H or a substituted or unsubstituted hydrocarbon residue or heterocyclic group, or R.sup.1 and R.sup.2 may, taken together with the adjacent N atom, form a heterocyclic group, and R.sup.3 is a substituted or unsubstituted hydrocarbon residue, have antimitotic, antitumor and antimicrobial activities.