The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 1981
Filed:
Aug. 01, 1979
Applicant:
Inventors:
Kiro Asano, Kukizaki, JP;
Humio Tamura, Kukizaki, JP;
Hiromitsu Tanaka, Tokyo, JP;
Satoru Enomoto, Fujisawa, JP;
Assignee:
Kureha Kagaku Kogyo Kabushiki Kaisha, Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07J / ; A61K / ;
U.S. Cl.
CPC ...
2603975 ; 424238 ; 2603974 ;
Abstract
The Chlorambucil derivatives are novel compounds having the formula (I). ##STR1## wherein R represents a hydrogen atom or an acyl group such as ##STR2## and n is 1 or 2. The Chlorambucil derivatives can be produced by binding Chlorambucil to hydroxyl group at 17-position of estradiol or its derivative in the presence of a binding agent selected from the group consisting of compounds having the formula