The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 1981

Filed:

Feb. 29, 1980
Applicant:
Inventors:

Lucien Nedelec, Le Raincy, FR;

Vesperto Torelli, Maisons-Alfort, FR;

Robert Fournex, Paris, FR;

Colette Tournemine, Livry-Gargan, FR;

Assignee:

Roussel Uclaf, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07J / ;
U.S. Cl.
CPC ...
424241 ; 26023957 ; 2603971 ;
Abstract

Novel 7-alkyl-.DELTA..sup.4 -17.alpha.-pregnene-3-ones of the formula ##STR1## wherein R is selected from the group consisting of saturated and unsaturated alkyl of 2 to 8 carbon atoms, cycloalkyl alkyl of 4 to 8 carbon atoms and arylalkyl of 7 to 12 carbon atoms and X and Y form the group ##STR2## or X is OH and Y is ##STR3## and M is selected from the group consisting of hydrogen, alkali metal and NH.sub.4 and the wavy line indicates the .alpha.- or .beta.-position or mixtures thereof having aldosterone antagonistic activity and increased hydrosodium diuresis with organic potassium conservation while devoid of secondary hormonal effects and their preparation.


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