The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 1981
Filed:
Mar. 18, 1980
Nobuo Yokoo, Sayama, JP;
Toshihito Mori, Higashimurayama, JP;
Kowa Company, Limited, Aichi, JP;
Abstract
The specification describes an economical process for the preparation of immunoglobulin for intravenous administration. An immunoglobulin can be, in accordance with the process, purified by a combination of a fractional precipitation method and an affinity chromatography. As a precipitant, divalent or trivalent metal salts are used and a complex of human IgG and a polyhydroxy polymeric compound is employed as an adsorbent. Purified immunoglobulin contains little or no aggregated or partially denatured globulin which is believed to cause anaphylaxis when administered intravenously. Prior art techniques cannot economically provide immunoglobulin in such a purified form and only intramuscular injections were feasible. Intravenous administrations allow immunoglobulin to be dosed in a larger amount and to act much faster than intramuscular injections.