The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 1981
Filed:
Apr. 16, 1979
Applicant:
Inventor:
Tetsuo Suami, Musashino-shi, Tokyo, JP;
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07H / ;
U.S. Cl.
CPC ...
424180 ; 536 22 ; 536 18 ; 536 53 ; 536 / ;
Abstract
Novel nitrosourea derivatives are provided which possess a high level of inhibitory activity against leukemia and tumors and other are therefore useful for pharmaceutical purposes. The compounds have the structure: ##STR1## wherein one of X and Y represents a hydroxyl and another of them represents a group --NHCONNOCH.sub.2 CH.sub.2 Cl; R represents a hydrogen, alkyl or aryl; and .about. represents a single bond which may be in the .alpha.- or .beta.-stereochemical configuration and are prepared by nitrosating a corresponding urea compound with a nitrosating agent in a manner known per se.