The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 1981

Filed:

Jun. 22, 1979
Applicant:
Inventor:

Patrick Mattock, Botley, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
2041 / ; 2042 / ; 2323 / ; 424 12 ;
Abstract

PCT No. PCT/GB78/00038 Sec. 371 Date June 22, 1979 Sec. 102(e) Date June 22, 1979, PCT Filed Nov. 10, 1978 PCT Pub. No. WO 79/00299 PCT Pub. Date May 31, 1979. The invention is concerned with purification of Factor VIII containing solutions, such as blood plasma, by continuous flow electrophoresis. Hitherto, purification of such solutions has been performed by methods such as cryoprecipitation which however have the disadvantages of poor recovery. In our invention, this problem is overcome by adjusting the pH of a Factor VIII containing solution to be in a range where the stability of Factor VIII is not adversely affected (e.g. 6 to 9) and then subjecting the solution to continuous flow electrophoresis to give purified Factor VIII fractions. If desired, the fractions may be further purified.


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