The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 1980

Filed:

May. 14, 1979
Applicant:
Inventors:

Kenji Tsujihara, Urawa, JP;

Masakatsu Ozeki, Wako, JP;

Yoshihisa Arai, Urawa, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07H / ; A61K / ;
U.S. Cl.
CPC ...
424180 ; 536 22 ; 536 53 ; 536 18 ;
Abstract

A nitrosourea compound of the formula: ##STR1## wherein R.sup.1 is an alicyclic group having 3 to 6 carbon atoms, phenyl, phenyl substituted with one to substituents selected from halogen, lower alkyl, lower alkoxy, hydroxy and nitro, or a heteromonocyclic group selected from oxiranyl, tetrahydrofuryl, 1,3-dioxolanyl, 1,4-dioxanyl, morpholino, tetrahydro-S,S-dioxo-thienyl, furyl, thienyl and pyridyl; R.sup.2 is aldopentofuranosyl, aldo-pentopyranosyl, aldo-hexopyranosyl or O-aldo-hexopyranosyl-(1.fwdarw.4)-aldo-hexopyranosyl; and A is a single bond or straight or branched alkylene having one to 3 carbon atoms, is prepared by nitrosation of a compound of the formula: ##STR2## wherein R.sup.1, R.sup.2 and A are the same as above. Said nitrosourea compound is useful as an anti-tumor or anti-leukemic agent however, effectiveness in human beings has not yet been demonstrated.


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Tsujihara, Kenji. (1980). Novel nitrosourea compounds and process for preparing the same (U.S. Patent No. 4241052). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4241052

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