The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 1980
Filed:
Sep. 12, 1978
Applicant:
Inventors:
Duane L Venton, Villa Park, IL (US);
Guy C Le Breton, Chicago, IL (US);
Steven E Enke, Lutz, FL (US);
Assignee:
The University of Illinois Foundation, Urbana, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ;
U.S. Cl.
CPC ...
424305 ; 560121 ; 562503 ; 424319 ;
Abstract
Novel azaprostanoic acid analogs of the formula ##STR1## wherein: R is C.sub.1 to C.sub.8 alkyl or benzyl; and a has a value of from 0 to 6 inclusive, and their pharmaceutically acceptable salts and esters. Preferred 13-aza and 15-aza compounds are active in the inhibition of arachidonic acid-induced platelet aggregation and, more specifically, are direct and specific antagonists of the activity of prostaglandin H.sub.2 and thromboxane A.sub.2.