The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 1980
Filed:
Oct. 31, 1979
Applicant:
Inventors:
Paul F Wiley, Kalamazoo, MI (US);
David J Houser, Portage, MI (US);
Assignee:
The Upjohn Company, Kalamazoo, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
2603403 ; 424278 ;
Abstract
Novel antibiotics, 7(R)-0-alkylnogalarols, prepared by acidic alcoholysis of nogalamycin of nogalarol, which are active against various microorganisms, for example, Bacillus subtilis, Streptococcus pyogenes, Sarcina lutea, Bacteroides fragilis, Clostridium perfringens, and Mycobacterium avium. Thus, they can be used to inhibit the growth of the above microorganisms in various environments. Further, the invention compounds possess unexpected superior activity against P388 leukemia infection in laboratory mice. Thus, the compounds of the invention can be used to treat laboratory mice infected with P388 leukemia.