The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 1980

Filed:

Jul. 26, 1978
Applicant:
Inventors:

Alexandr P Skoldinov, Moscow, SU;

Arkady M Likhosherstov, Moscow, SU;

Vitaly P Peresada, Moscow, SU;

Assignee:

Other;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
544349 ; 424250 ;
Abstract

1,2,3,4-Tetrahydropyrrolo-[1,2-a]-pyrazine of the formula: ##STR1## is disclosed together with a method for preparing the same which comprises reducing 3,4-dihydropyrrolo-[1,2-a]-pyrazine, in a medium of an organic solvent, by way of hydrogenation with hydrogen or complex hydrides of metals. When using hydrogen said hydrogenation is effected in the presence of a catalyst of the group of platinum. The desired product is then isolated from the reaction mixture. The resulting 1,2,3,4-tetrahydropyrrolo-[1,2-a]-pyrazine may be used as the starting product for the synthesis of physiologically active compounds such as octahydropyrrolo-[1,2-a]-pyrazine which serves as the basis for the preparation of coronary-dilating and neuroleptic compounds. The method for preparing 1,2,3,4-tetrahydropyrrolo-[1,2-a]-pyrazine is technologically simple and may be readily implemented on a commercial scale.


Find Patent Forward Citations

Loading…