The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 1980

Filed:

Nov. 09, 1977
Applicant:
Inventors:

Jean-Bernard Ducep, Paris, FR;

Daniel Farge, Thiais, FR;

Gerard Ponsinet, Sucy-en-Brie, FR;

Daniel Reisdorf, Thiais, FR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07G / ;
U.S. Cl.
CPC ...
424180 ; 536 / ;
Abstract

Daunorubicin derivatives of the formula: ##STR1## wherein R.sub.1 represents a group of the formula: ##STR2## in which (i) X.sub.1 and X.sub.2 both represent oxygen or both represent sulphur and the symbols R.sub.3 each represent alkyl of 1 through 4 carbon atoms, phenyl or phenyl substituted in the para-position by methyl, methoxy or methylthio, or together form an alkylene radical of 2 through 4 carbon atoms, or (ii) one of X.sub.1 and X.sub.2 represents oxygen and the other represents sulphur and the symbols R.sub.3 together form an alkylene radical of 2 through 4 carbon atoms, and R.sub.4 represents hydrogen, alkyl of 1 through 4 carbon atoms or phenyl, and R.sub.2 represents hydrogen or trifluoroacetyl, are new compounds possessing anti-tumour properties.


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