The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 1980
Filed:
Dec. 18, 1978
Applicant:
Inventor:
Emil T Kaiser, Chicago, IL (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J / ; C07J / ;
U.S. Cl.
CPC ...
2602 / ; 2603971 ; 2603975 ; 2603972 ;
Abstract
The synthesis of 25-hydroxycholesterol and 1.alpha.,25-dihydroxycholesterol in which the sterol nucleus of an ester of hyodeoxycholic acid is stabilized by protection of the 3 and 6.alpha.-hydroxyl groups with alkyl groups, alkyl ether groups, preferably with the 3.beta.-methoxyethoxymethyl group or with the heterocyclic 2-tetrahydropyran group, then extending the chain from the carbon at the 24-position to a cyanide group at the 25-position and then subjecting the sterol so formed to a series of reactions by which it is transformed into 1.alpha.,25-dihydroxycholesterol or by a modified series of reactions to 25-hydroxycholesterol.