The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 1980
Filed:
Jul. 10, 1978
Applicant:
Inventor:
Harry Ferres, Epsom, GB;
Assignee:
Beecham Group Limited, , GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
424250 ; 2602391 ; 42424855 ; 424267 ; 424269 ; 424271 ;
Abstract
A class of esters of the penicillin, nafcillin have the general formula: ##STR1## wherein A is a C.sub.1 -C.sub.6 alkylene group substituted with one or two groups of formula --NR.sup.1 R.sup.2 and optionally further substituted with one or more methyl or ethyl groups, wherein R.sup.1 and R.sup.2 are the same or different and each is a C.sub.1 -C.sub.6 alkyl group or R.sup.1 and R.sup.2 together with the nitrogen atom to which they are attached form a saturated 5- or 6- membered heterocyclic ring. Upon oral administration, the esters are absorbed into the bloodstream where they are hydrolyzed to release the antibacterially active parent penicillin, nafcillin.