The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 1980
Filed:
Nov. 13, 1978
D Joe Baughman, Flemington, NJ (US);
Ann Lytwyn, New Brunswick, NJ (US);
Kurt Myrmel, Somerville, NJ (US);
Ortho Diagnostics Inc., Raritan, NJ (US);
Abstract
A quantitative method and composition for precipitating fibrin monomers from plasma in the presence of fibrinogen, with only a small amount, if any, of fibrinogen being precipitated. A buffered precipitating agent is provided having a pH in the range of 6.5.+-.0.5, the buffer being one having a pKa in the range of 6 to 7 and protamine sulfate at a level of 0.025 to 0.2% by weight. Suitable buffers are 2-(N-morpholino)ethanesulfonic acid, sodium phosphate, histidine, maleic acid and imidazole. Analysis of the amount of fibrin present can be made by analyzing for protein using preferably a basic urea solution containing sodium hydroxide and measuring the absorbance at 282 nanometers.