The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 1980
Filed:
Apr. 05, 1978
Applicant:
Inventor:
Francisco S Alvarez, Sunnyvale, CA (US);
Assignee:
Syntex (U.S.A.) Inc., Palo Alto, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07J / ;
U.S. Cl.
CPC ...
2602 / ; 2603971 ; 2602395 ; 26039745 ;
Abstract
This invention is a process for preparing 3-keto-androst-4-ene 17.alpha.-carboxylic acids, androsta-1,4-diene 17.alpha.-carboxylic acids and their 17.alpha.-esters by reacting a corresponding 21-hydroxypregn-4-ene-3,20-dione, 21-hydroxypregna-1,4-diene-3, 20-dione, or their 21-esters with an alkali metal carbonate base in a lower alkanol in the presence of oxygen. The 17.alpha.-esters are formed by reacting the 17.alpha.-carboxylic acid with a suitable alkylating agent.