The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 1980

Filed:

Dec. 13, 1978
Applicant:
Inventors:

Karl H Kingler, Lagen, DE;

Klause Thiemer, Hanau, DE;

Fritz Stroman, Offenbach, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07C / ;
U.S. Cl.
CPC ...
424316 ; 2603 / ; 26050111 ; 424319 ; 424282 ; 562401 ; 562444 ;
Abstract

There are prepare half amides (semi-amides) of unsaturated aliphatic dicarboxylic acids of the formula: ##STR1## where R.sub.1, R.sub.2 and R.sub.3 are the same or different and are hydrogen, halogen, a hydroxy group, a methyl group or a methoxy group or two of these together are a methylenedioxy group, R.sub.4 is hydrogen or a methyl group, R.sub.5, R.sub.6 and R.sub.7 independently are hydrogen or C.sub.1 -C.sub.4 alkyl groups and n is 0 or 1 and their salts with the proviso that in the case of the free acids N[2-(3-hydroxyphenyl)-2-hydroxyethyl]-maleic acid monoamide is excluded. The compounds have blood pressure raising activity and also have antidepressive activity.


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Kingler, Karl. (1980). Maleic acid halfamides having blood pressure raising activity (U.S. Patent No. 4191777). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4191777

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